Buffalo Bills vs Detroit Lions NFL Picks & NFL 2010 Predictions: The Detroit Lions face the Buffalo Bills at Ford Field in Detroit in tonight's week 4 2010 NFL predictions matchup. The Lions are 4-point NFL picks favorites in Vegas odds, but with first-string units for both teams playing limited snaps, you’ll want to take any Vegas NFL predictions with a grain of salt. The best Vegas style online sportsbook to bet the Lions or bet the Bills is Sportsbook.com. Take advantage of Sportsbook.com's $250 Signup up Bonus before the official 2010 NFL schedule kicks off, by then this NFL predictions bonus will be gone.
The Detroit Lions (2-1) have won two straight NFL predictions contests at Denver and vs. Cleveland. Quarterback Matthew Stafford, wide receiver Calvin Johnson and the rest of the first offensive unit is expected to play into the first quarter of tonight's final preseaon NFL picks matchup and then depart. Look for quarterback Shaun Hill to take over the offense early int eh NFL preidctions matchup and running back Aaron Brown, a second-year player from TCU to get most of the carries into the second half. Brown is a back worth watching in tonight's week 4 preseason NFL picks matchup as he scored two TDs against the Browns in week 3 of the 2010 NFL predictions season. Defensively, the Lions will be shuttling-in lots of second tier talent so look for some points to be scored, especially, in the second half of the NFL picks matchup
The Buffalo Bills (2-1) are also coming off two NFL predictions victories at home against the Colts and Bengals, in which in both they beat the Vegas NFL odds. Trent Edwards has cemented the starting QB job so expect him to be replaced early on in the NFL predictions matchup with Ryan Fitzpatrick and Brian Brohm. Fitzpatrick had a TD pass last week vs. the Bengals but you won’t see much offense. The Bills will also want to get a look at CJ Spiller, a rookie who has made an instant impact. He could put-up a score before he retires for the night. Defensively in tonight's NFL predictions matchup, the Bills reserves have held their own in the second halves of the last two NFL picks contests so you can expect them to hold their own against a less-than-average second-tier Lions’ attack.
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