Kansas City Chiefs look to win as home underdogs vs 49ers NFL Week 3 Picks & Odds

Kansas City Chiefs look to win as home underdogs vs 49ers NFL Week 3 Picks & NFL Vegas Odds - Two unfamiliar, non-conference opponents will meet as the San Francisco 49ers vs. Kansas City Chiefs in a NFL Week 3 Picks matchup. These two teams have only met twice since 2002, with the Chiefs winning the most recent game 41-0. Las Vegas odds have placed the 49ers as -3-point Spread favorites on the road.

San Francisco (0-2) is coming off a NFL Picks Loss 25-22 last-second loss to the New Orleans Saints on MNF. The 49ers came back from a 22-14 deficit late to tie the game on an impressive drive only to lose as Drew Brees drove the Saints down the field for a game-winning kick. Alex Smith played well at quarterback, especially in the second half, consistently finding tight end Vernon Davis and receiver Josh Morgan for big plays. Davis is a match-up problem for most teams, with a combination of size and speed, and Morgan is favorite target of Smith. Frank Gore also had an impact on the game as a running back and receiver, gaining over 160 all-purpose yards. He will be an important part of the game plan against the Chiefs active front-seven.

The Chiefs (2-0) NFL Vegas Odds +3 home underdogs are off to a surprising and fast start. They used special teams to leap frog the Chargers in week one and ground out a victory against the Cleveland Browns last week, 16-14, getting three field goals from Ryan Succop. Defensively, Kansas City has been better than advertised. Linebacker Derrick Johnson has been a force inside with 19 tackles and a forced fumble, and Eric Berry has provided an infusion of talent in the secondary. The biggest difference, however, might be in the game planning provided by defensive coordinator Romeo Crennel. Crennel has impacted how the team plays and, in week one, was crucial in containing tight end Antonio Gates, double-teaming the Chargers tight end after he ripped the KC secondary for big gains in the first half. Crennel must game plan around San Francisco’s Davis in a similar fashion, forcing the 49ers to look elsewhere for offense.

With Smith coming into his own in the second half against the Saints, the 49ers might look to air things out against the Chiefs. KC needs to find a way to get some sacks and pressures and their main task will be shut down Gore. This game feels like a trap for anyone playing the Vegas NFL Lines and KC has more than enough weapons to cover the Point Spread set by Vegas Lines makers and win outright at home in a mild upset. NFL Odds makes have listed the total at 37 points.

Last time these two teams met the Chiefs shut out the 49ers, 41-0, at home in 2006. They will try to do the same in this NFL Week 3 Picks matchup. Vegas-spreads.com recommends you Make you NFL Picks Week 3 Bet on Kansas City Chiefs on the NFL Moneyline +120. If you are going to make a NFL Picks bet on this game, take advantage of Betus.com 100% Sign up Bonus this weekend.

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