Philadelphia vs San Francisco 2010 NFL Week 5 Predictions & Vegas Betting Odds

San-Fransisco-49ersPhiladelphia vs San Francisco 2010 NFL Week 5 Predictions & Vegas Betting Odds: With Michael Vick out with a rib injury, the Philadelphia Eagles find themselves as +3½(-120) point NFL predictions underdog on the road against the winless San Francisco 49ers in a NFC conference NFL week 5 Vegas betting odds contest.

The Eagles3 (2-2) struggled on offense after Vick’s injury in a 17-12 NFL predictions loss to the Washington Redskins and Donovan McNabb. At quarterback, Kevin Kolb returns as the starter, though his early numbers have been less than impressive. He’ll need to find his groove early in this NFL week 5 predictions contest to avoid pressing. The Eagles did receive good news this week as running back LeSean McCoy is expected to be a full go despite a cracked rib. McCoy has been a consistent threat as a runner and receiver and should expect to carry a full load in today's week 5 NFL picks battle. Brent Celek, the Eagles Pro Bowl tight end, should benefit from Kolb’s return, while DeSean Jackson will still look to go deep.

The 49ers are 0-4 and their latest NFL picks disappointment came in the last seconds of a 16-14 NFL predictions loss to the Atlanta Falcons. The defense of San Francisco, thought to be a strength, is ranked in the bottom half of the league in both passing and rushing defense. The defense has generated just six sacks and only four turnovers, two interceptions each by two players. Patrick Willis is still a beast at linebacker, leading the team in tackles, but others have been disappointing.

With Kolb in the line-up, the complexion of the NFL week 5 predictions contest changes tremendously. The 49ers will want to harass Kolb, meaning the outside linebackers must rush hard, and San Francisco will be looking for a turnover. However, Kolb was good enough to be the starter at the beginning of the 2010 NFL picks season and he will make enough plays to cover the spread and keep the 49ers winless in 2010.

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